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Recent Progress in Research on Ribosome Inactivating Proteins

[ Vol. 11 , Issue. 1 ]


T. B. Ng, Jack Ho Wong and Hexiang Wang   Pages 37 - 53 ( 17 )


The intent of this article is to review recent literature on ribosome inactivating proteins (RIPs) including isolation and characterization of new RIPs, studies on the crystal structures and mechanisms of actions of RIPs, the use of saporin-based neurotoxins to selectively lesion cholinergic neurons in neuroscience research, and the use of RIP-based conjugates and immunotoxins in anticancer therapy.

, Recent, Progress, in, Research, on, Ribosome, Inactivating, Proteins


School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong, China.

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