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A Bird's-Eye View of Proteomics

Author(s):

Vladimir N. Uversky*, Mohammed F. Alghamdi and Elrashdy M. Redwan*  

Abstract:


Modern protein science is broadening horizons by moving toward the systemic description of proteins in their natural habitats. This implies a transition from a classical reductionist approach associated with consideration of the unique structure and specific biological activity of an individual protein in a purified form to studying entire proteomes and their functions. This mini-review provides a brief description of structural, functional, and expression proteomics, the dark proteome (or unfoldome), and some of the tools utilized in the analyses of proteomes.

Keywords:

Proteome, proteomics; protein expression, protein function, intrinsically disordered proteins, dark proteome, unfoldome; unfoldomics

Affiliation:

Biological Sciences Department, Faculty of Science, and Laboratory Department, University Medical Services Center, King Abdulaziz University, Jeddah, Biological Sciences Department, Faculty of Science, and Laboratory Department, University Medical Services Center, King Abdulaziz University, Jeddah, Biological Sciences Department, Faculty of Science, and Laboratory Department, University Medical Services Center, King Abdulaziz University, Jeddah



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