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GRASP55: A Multifunctional Protein

Author(s):

Hongrong Wu, Tianjiao Li and Jianfeng Zhao*   Pages 1 - 9 ( 9 )

Abstract:


GRASP55 was first found as a Golgi cisternae stacking protein. Due to the crucial role of Golgi in vesicular trafficking and protein modification, GRASP55 was found to function in these two aspects. Further investigation showed that GRASP55 also participates in unconventional secretory pathway under stress. Far more than that, GRASP55 is involved in autophagy initiation and autophagosome maturation, as well as cell activity.

Keywords:

GRASP55, Golgi, Autophagy, Unconventional secretory pathway, Vesicular trafficking, Golgin45

Affiliation:

Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hengyang, Hengyang Medical College, University of South China, Hengyang, Institute of Neuroscience, Hengyang Medical College, University of South China, Hengyang



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