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Regulation of Probiotics on Metabolism of Dietary Protein in Intestine

Author(s):

Xiao-Pei Peng, Cunxi Nie, Wen-Yi Guan, Li-Dong Qiao, Lin Lu and Shou-Jun Cao*   Pages 1 - 6 ( 6 )

Abstract:


Proteins are indispensable components of living organisms, which are derived mainly from dietary proteins through metabolism. Dietary proteins are degraded by endogenous digestive enzymes to di- or tri-peptides and free amino acids (AAs) in the small intestine lumen and then absorbed into blood and lymph through intestinal epithelial cells via diverse transporters. Microorganisms are involved not only the proteins catabiosis, but also the AAs, especially essential AAs, anabolism. Probiotics regulate these processes by providing exogenous proteases and AAs and peptide transporters, and reducing hazardous substances in the food and feed. But the core mechanism is a modulating of the composition of intestinal microorganisms through their colonization, exclusion of pathogens. The other effects of probiotics are associated with normal intestinal morphology, which implies the enterocytes secrete more enzymes to decompose dietary proteins and absorb more nutrients.

Keywords:

Regulation, probiotics, dietary protein, amino acids (AAs), metabolism, intestinal flora, intestinal epithelial cells (IECs)

Affiliation:

Department of Animal Husbandry and Veterinary Medicine, Beijing Vocational College of Agriculture, Beijing, College of Animal Science and Technology, Shihezi University, Shihezi, Department of Animal Husbandry and Veterinary Medicine, Beijing Vocational College of Agriculture, Beijing, Department of Animal Husbandry and Veterinary Medicine, Beijing Vocational College of Agriculture, Beijing, Animal Science and Technology College, Beijing University of Agriculture, Beijing, Department of Animal Husbandry and Veterinary Medicine, Beijing Vocational College of Agriculture, Beijing



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