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The Immune System Regulation in Sepsis: From Innate to Adaptive

Author(s):

Yue Qiu, Guo-wei Tu, Min-jie Ju, Cheng Yang and Zhe Luo*   Pages 1 - 17 ( 17 )

Abstract:


Sepsis, which is a highly heterogeneous syndrome, can result in death as a consequence of a systemic inflammatory response syndrome. The activation and regulation of immune system play a key role in the initiation, development and prognosis of sepsis. Due to the different periods of sepsis when the objects investigated were incorporated, clinical trials often exhibit negative results and even contrary. Thus, in this review we aim to sort out the current knowledge in how immune cells play the role during sepsis.

Keywords:

sepsis, innate immunity, adaptive immunity, inflammation, protein

Affiliation:

Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, Zhongshan Hospital, Fudan University - Urology Shanghai, Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032



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