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Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers

[ Vol. 20 , Issue. 3 ]

Author(s):

Liang Zhang, Tzi Bun Ng, Jenny Ka Wing Lam, Shi Wei Wang, Lixing Lao, Kalin Yanbo Zhang and Stephen Cho Wing Sze*   Pages 277 - 284 ( 8 )

Abstract:


We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.

Keywords:

Medicinal yam, proteins, peptides, anti-oxidation, anti-microbial, anti-cancer, immunomodulation, menopause.

Affiliation:

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, Department of Biology, Faculty of Science, Hong Kong Baptisit University, Hong Kong SAR



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