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Transforming Growth Factor-Beta Family: Advances in Vascular Function and Signaling

[ Vol. 19 , Issue. 12 ]

Author(s):

Sebastian Gatica, Claudio Cabello-Verrugio and Felipe Simon*   Pages 1164 - 1171 ( 8 )

Abstract:


This review includes a comprehensive, but succinct, summary on the essentials of TGF- β structure, family members, receptors, and intracellular mediators. Also provided is a select list of original publications that report novel roles and facets of TGF-β in vascular function and signaling in the contexts of health and disease.

Keywords:

TGF, vascular, angiogenesis, hypertension, EndMT, fibrosis.

Affiliation:

Laboratory of Integrative Physiopathology, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas and Facultad de Medicina, Universidad Andres Bello, Santiago, Millennium Institute on Immunology and Immunotherapy, Santiago, Laboratory of Integrative Physiopathology, Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas and Facultad de Medicina, Universidad Andres Bello, Santiago

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